Poster Presentation Australian Society for Microbiology Annual Scientific Meeting 2014

Schistosoma Serology – An Evaluation of NovaTec Schistosoma mansoni IgG ELISA (#454)

Bruce Wong 1 2 , Sarah Gan 1 2 , James Ho 2 , Noel Fisher 2 , Archie Darbar 2
  1. Medical and Biomedical Sciences, Faculty of Science, University of Technology, Sydney, Sydney, New South Wales, Australia
  2. Department of Microbiology & Infectious Diseases, Pathology North, Royal North Shore Hospital, St Leonards, New South Wales, Australia

Schistosomiasis is a tropical, intravascular infection caused by parasitic trematode worms from the Schistosomitidae family. The three main species that cause the disease in humans are Schistosoma haematobium, S. mansoni and S. japonicum.

Schistosomiasis infects approximately 200 million people worldwide and causes an estimated 12,000 to 200,000 deaths per year. Commonly found in places with poor sanitation, the parasites penetrate human skin and migrate to the liver, bladder and kidneys.

The chronic form of disease of Schistosomiasis may cause kidney failure, liver damage, infertility or bladder cancer, as well as learning difficulties in children. Schistosomiasis is readily treated thus the importance for accurate and reliable diagnostic techniques.

In our study we evaluate the NovaTec Schistosoma mansoni IgG ELISA enzyme immunoassay in its performance to determine the presence of IgG class antibodies against Schistosoma mansoni using the Bio-Rad Evolis.