Helicobacter pylori is a spiral shaped gram negative bacterium which usually resides in the mucous layer of the human digestive tract. H.pylori infects over 30% of the world’s population and is the primary cause of duodenal and peptic ulcers. It is also known to cause chronic gastritis, gastric cancer and lymphoma. . The aim of this study was to make the H. pylori stool antigen test available as an in house test at Dorevitch Pathology.
The LIAISON® H. pylori SA assay is a chemiluminescent immunoassay, which operates as a 2 step sandwich for the qualitative determination of H. pylori stool antigens, on the LIAISON analyser. The analyser operates autonomously reducing operator variability between each sample, delivering more efficient results. This test can be used for the primary identification of H. pylori, and can assist as a useful tool in monitoring treatment response in post therapy patients.
Detection of H. pylori can be achieved by a variety of different methods including the urea breath test, blood test, biopsy and stool antigen detection.
In this study we compared the LIASION H. pylori SA® with the Meridian Bioscience HpSA. Out of the 75 samples tested, the results of the LIASION H. pylori SA® favourably compared to the current method used for reporting results.